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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHTF18
All Species:
35.45
Human Site:
S421
Identified Species:
60
UniProt:
Q8WVB6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVB6
NP_071375.1
975
107383
S421
E
A
A
T
Q
M
E
S
V
L
G
A
G
G
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087813
975
107675
S421
E
A
A
T
Q
M
E
S
V
L
G
A
G
G
K
Dog
Lupus familis
XP_547205
952
105405
S385
E
A
A
T
Q
M
E
S
V
L
G
A
G
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIW9
969
108119
S416
E
A
A
T
Q
M
E
S
V
L
G
V
G
G
R
Rat
Rattus norvegicus
NP_001099243
968
107973
S414
E
A
A
T
Q
M
E
S
V
L
G
A
G
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519056
506
55652
G74
P
F
S
M
S
R
A
G
R
A
L
G
A
R
V
Chicken
Gallus gallus
XP_414833
951
106607
S405
E
A
A
T
Q
M
K
S
V
L
G
A
E
E
K
Frog
Xenopus laevis
Q6NU40
1000
113204
S443
E
A
A
T
Q
M
K
S
V
L
G
V
D
E
R
Zebra Danio
Brachydanio rerio
NP_001103572
957
108656
S420
D
T
A
T
Q
M
K
S
V
L
G
A
N
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_787969
993
111731
S474
E
N
G
T
Q
M
S
S
V
L
N
E
D
K
R
Honey Bee
Apis mellifera
XP_001122463
755
86984
E324
I
E
I
N
A
S
D
E
R
S
P
D
T
F
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780624
1005
112781
S441
Q
S
S
I
Q
M
T
S
V
L
T
P
D
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_171966
954
107988
S399
L
D
V
V
Q
M
N
S
V
T
A
D
S
R
P
Baker's Yeast
Sacchar. cerevisiae
P49956
741
84355
K309
A
P
S
L
E
K
L
K
P
F
C
E
I
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
73
N.A.
76
77.2
N.A.
20.2
53.7
53.4
46.6
N.A.
32.4
27.8
N.A.
34.6
Protein Similarity:
100
N.A.
95.9
79.6
N.A.
81.7
82.7
N.A.
29.8
68.7
71
63.3
N.A.
52.5
45.3
N.A.
54.1
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
0
80
66.6
66.6
N.A.
46.6
0
N.A.
33.3
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
6.6
86.6
80
80
N.A.
53.3
13.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
58
0
8
0
8
0
0
8
8
43
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
8
0
0
0
0
15
22
0
0
% D
% Glu:
58
8
0
0
8
0
36
8
0
0
0
15
8
22
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
58
8
36
36
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
0
0
8
22
8
0
0
0
0
0
8
36
% K
% Leu:
8
0
0
8
0
0
8
0
0
72
8
0
0
0
0
% L
% Met:
0
0
0
8
0
79
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
8
0
0
0
8
0
8
0
0
% N
% Pro:
8
8
0
0
0
0
0
0
8
0
8
8
0
0
8
% P
% Gln:
8
0
0
0
79
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
15
0
0
0
0
15
43
% R
% Ser:
0
8
22
0
8
8
8
79
0
8
0
0
8
0
0
% S
% Thr:
0
8
0
65
0
0
8
0
0
8
8
0
8
0
0
% T
% Val:
0
0
8
8
0
0
0
0
79
0
0
15
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _